RNA Data Analysis and Research
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RADAR is a web-based server for RNA data analysis and research. RADAR can align structure-annotated RNA sequences so that both sequence and structure information are taken into consideration. This server is capable of performing database search, multiple structure alignment, and pair-wise structure comparison. In addition, RADAR provides two salient features: (1) constrained alignment of RNA secondary structures, and (2) prediction of the consensus structure for a set of RNA sequences. RADAR assists scientists in performing many important RNA mining operations, including understanding the functionality of RNA sequences, the detection of structural RNA motifs and the clustering of RNA molecules, among others. RADAR uses the RSmatch algorithm for alignment. Standalone RSmatch v2.0, which is RADAR, is freely available for interested researchers.
1. J. Liu, J.T.L. Wang, J. Hu and B. Tian. A method for aligning RNA secondary structures and its application to RNA motif detection. BMC Bioinformatics, 6:89, 2005.
2. M. Khaladkar, V. Bellofatto, J.T.L. Wang, B. Tian and B.A. Shapiro. RADAR: a web server for RNA data analysis and research. Nucleic Acids Research, 35:W300-W304, 2007.
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